Abstract: Using the response functions of the growth and yield of crops to temperature and precpitation,the calculating model of the variability of the yield of major grain crops of Northeast China is founded.the variability of the grain yield in various parts of Northeast China is analysed in association with variable combined condition (temperature change 1-20℃ and pricipitation change 10%-20%).The agricultural countermeasures to the climate change are also put forward.The results show that the impact of climate change on the yield of grain crops and legumes in various parts of the Area is relative great and the region difference is evident. With 10C fluctuation of temperature,there will be 2%-40% variation per unit grain yield in the most part,and the broadest range of the variation is in the northern and eastern mountationous area,the variation is vary slightly in the south parts of Liaoning Province.In the western area,the yield of the crops will incraese by about 10% with an increase of precipitation 10%,where as the crops yield will drops by about 8% in the southeastern part.Different agricultural countermeasures should be taken in various parts to adapt the climate change in the future.